It has been shown that light deprivation affects synaptic connections of ganglion cells in the mammalian retina , but little is known about impacts of visual deprivation on bipolar cell development 目前已經(jīng)有人證實(shí),初生時(shí)期失去光照會(huì)影響哺乳動(dòng)物神經(jīng)節(jié)細(xì)胞的突觸連結(jié),但是卻很少有對(duì)雙極細(xì)胞影響的相關(guān)研究。
But how could the glia in our experiment be detecting the neuronal firing , given that the axons made no synaptic connections with the glia and the axonal glia were nowhere near the synapse 不過軸突并沒有突觸與神經(jīng)膠細(xì)胞接觸,而且軸突上的神經(jīng)膠細(xì)胞又離突觸那麼遠(yuǎn),我們實(shí)驗(yàn)中的神經(jīng)膠細(xì)胞如何才能夠偵測(cè)神經(jīng)元的活性呢?
And he wonders whether the epilepsy that can occur in stroke and trauma patients , often years after the injury , results from unsuccessful attempts by the progeny of neural stem cells to make synaptic connections with other cells in the damaged region 而且他漫想是否癲癇會(huì)出現(xiàn)在中風(fēng)和創(chuàng)傷病人,常常是受傷之后的許多年,原因是神經(jīng)干細(xì)胞的子代嘗試與損傷區(qū)域的細(xì)胞建立突觸連接失敗。
Moving from hebb ' s theory to sorting out the actual mechanics of this process , however , one again confronts the fact that the enzymes and proteins that strengthen or weaken synaptic connections during brain wiring must be synthesized from specific genes 不過,從赫柏的理論到?清整個(gè)過程中的實(shí)際機(jī)制,會(huì)再度面臨一個(gè)事實(shí),那就是在腦建立線路的過程中,那些會(huì)強(qiáng)化或削弱突觸連結(jié)的酵素與蛋白質(zhì),都必須經(jīng)由特定的基因來合成。
The results suggest that visual experience has a facilitating effect on morphological differentiation of bipolar cells , and early mature bipolar cells could provide light dependent signals to guide synaptic connections of ganglion cells in the inner retina 本篇結(jié)果證明了視覺經(jīng)驗(yàn)可促進(jìn)雙極細(xì)胞的形態(tài)發(fā)育,并可進(jìn)而推論早期成熟的雙極細(xì)胞提供了光傳入視網(wǎng)膜的訊號(hào),再進(jìn)一步去影響內(nèi)層視網(wǎng)膜中神經(jīng)節(jié)細(xì)胞在發(fā)育過程中的突觸連結(jié)。